The aim of the paper was to estimate the effect of experimental cerebral ischemia on metabolic characteristics of parietal cortex neurons. The experiments were carried out on 12 laboratory male rats. Cerebral ischemia was modeled with bilateral joint carotid arteries with durations of 60 minutes under intravenous thiopental anesthesia (40-50 mg / kg). The rats were decapitated and the samples of the brain parietal cortex were prepared for histological and histochemical examination in combination with morphometry to examine the 5th layer inner pyramidal neurons. It was increased the number of pathological forms and shrinkage of the 5th layer inner pyramidal neurons after cerebral ischemia in rats. The histochemical examination was revealed the inhibition of NADH-, glucose-6-phosphate dehydrogenase and succinate dehydrogenases as well as activation of lactate dehydrogenase and acid phosphatase. Cerebral ischemia induces deep histological and histochemical changes in the parietal cortex neurons in rats, including shrinkage of parietal cortex neurons and disturbances of their energy metabolism.
| Published in | Bioprocess Engineering (Volume 2, Issue 1) |
| DOI | 10.11648/j.be.20180201.11 |
| Page(s) | 1-5 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2018. Published by Science Publishing Group |
Cerebral Ischemia, Parietal Cortex, Neurons
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APA Style
Lizaveta Igorevna Bon, Nataliya Yevgenyevna Maksimovich, Sergey Michailovich Zimatkin. (2018). Effects of Experemental Cerebral Ishemia on Metabolic Characteristics of Parietal Cortex Neurons. Bioprocess Engineering, 2(1), 1-5. https://doi.org/10.11648/j.be.20180201.11
ACS Style
Lizaveta Igorevna Bon; Nataliya Yevgenyevna Maksimovich; Sergey Michailovich Zimatkin. Effects of Experemental Cerebral Ishemia on Metabolic Characteristics of Parietal Cortex Neurons. Bioprocess Eng. 2018, 2(1), 1-5. doi: 10.11648/j.be.20180201.11
AMA Style
Lizaveta Igorevna Bon, Nataliya Yevgenyevna Maksimovich, Sergey Michailovich Zimatkin. Effects of Experemental Cerebral Ishemia on Metabolic Characteristics of Parietal Cortex Neurons. Bioprocess Eng. 2018;2(1):1-5. doi: 10.11648/j.be.20180201.11
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Download@article{10.11648/j.be.20180201.11,
author = {Lizaveta Igorevna Bon and Nataliya Yevgenyevna Maksimovich and Sergey Michailovich Zimatkin},
title = {Effects of Experemental Cerebral Ishemia on Metabolic Characteristics of Parietal Cortex Neurons},
journal = {Bioprocess Engineering},
volume = {2},
number = {1},
pages = {1-5},
doi = {10.11648/j.be.20180201.11},
url = {https://doi.org/10.11648/j.be.20180201.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.be.20180201.11},
abstract = {The aim of the paper was to estimate the effect of experimental cerebral ischemia on metabolic characteristics of parietal cortex neurons. The experiments were carried out on 12 laboratory male rats. Cerebral ischemia was modeled with bilateral joint carotid arteries with durations of 60 minutes under intravenous thiopental anesthesia (40-50 mg / kg). The rats were decapitated and the samples of the brain parietal cortex were prepared for histological and histochemical examination in combination with morphometry to examine the 5th layer inner pyramidal neurons. It was increased the number of pathological forms and shrinkage of the 5th layer inner pyramidal neurons after cerebral ischemia in rats. The histochemical examination was revealed the inhibition of NADH-, glucose-6-phosphate dehydrogenase and succinate dehydrogenases as well as activation of lactate dehydrogenase and acid phosphatase. Cerebral ischemia induces deep histological and histochemical changes in the parietal cortex neurons in rats, including shrinkage of parietal cortex neurons and disturbances of their energy metabolism.},
year = {2018}
}
TY - JOUR T1 - Effects of Experemental Cerebral Ishemia on Metabolic Characteristics of Parietal Cortex Neurons AU - Lizaveta Igorevna Bon AU - Nataliya Yevgenyevna Maksimovich AU - Sergey Michailovich Zimatkin Y1 - 2018/04/03 PY - 2018 N1 - https://doi.org/10.11648/j.be.20180201.11 DO - 10.11648/j.be.20180201.11 T2 - Bioprocess Engineering JF - Bioprocess Engineering JO - Bioprocess Engineering SP - 1 EP - 5 PB - Science Publishing Group SN - 2578-8701 UR - https://doi.org/10.11648/j.be.20180201.11 AB - The aim of the paper was to estimate the effect of experimental cerebral ischemia on metabolic characteristics of parietal cortex neurons. The experiments were carried out on 12 laboratory male rats. Cerebral ischemia was modeled with bilateral joint carotid arteries with durations of 60 minutes under intravenous thiopental anesthesia (40-50 mg / kg). The rats were decapitated and the samples of the brain parietal cortex were prepared for histological and histochemical examination in combination with morphometry to examine the 5th layer inner pyramidal neurons. It was increased the number of pathological forms and shrinkage of the 5th layer inner pyramidal neurons after cerebral ischemia in rats. The histochemical examination was revealed the inhibition of NADH-, glucose-6-phosphate dehydrogenase and succinate dehydrogenases as well as activation of lactate dehydrogenase and acid phosphatase. Cerebral ischemia induces deep histological and histochemical changes in the parietal cortex neurons in rats, including shrinkage of parietal cortex neurons and disturbances of their energy metabolism. VL - 2 IS - 1 ER -
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